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pentobarbital will lessen the extent or impact of imatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.pentobarbital will minimize the extent or effect of theophylline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will minimize the extent or result of lorla